RWD Photometry System

Detecting the activity change of neurons in the central nervous system in real-time, the fiber photometry sums up the overall fluorescence of neurons to express their overall activity without reflecting on the activity of individual neurons.

Based on the reference channel of 410 nm wavelength, RWD Fiber Photometry System adopts 470 nm and 560 nm dual-wavelength excitation reducing the background noise effectively. The significance of the reference channel lies in increasing self-control, reducing spontaneous fluorescence, eliminating signal artifacts caused by animal’s intense exercise and fiber winding, expressing two kinds of proteins at the same site, detecting levels of calcium change in different groups of neurons, and truly realizing the recording and analysis of dual-color fluorescence signals.

Advantages:

  • Up to 7 channels. Suitable for high-throughput calceium signal acquisition or simultaneous recording of multiple nervous nuclei

  • When the external event is marked, time is automatically input toachieve synchronous recording with the behavioral video. The synchronous accuracy of external stimulus time is up to lOms, which ensures the real-time synchronization of animal behavior and calcium fluorescence signal changes efficiently

  • Two kinds of LED excitation light sources and one kind of background de-noising LED light source enable more accurate fluorescence signal change acquisition

  • Four fluorescence modes are optional to meet various experimental requirements.

  • The CMOS industrial camera with high performance and low noise collects all calcium fluorescence signals of multichannel and multi-wavelength;

  • Low spontaneous fluorescence and better stability with stainless steel metal pin. Independent multi mode fiber bundles can avoid the interference of fluorescent signals in multiple channels perfectly;

  • Reliable performance and long lifespan over 10,000 hours