Fiber Photometry System

R810- Dual Color Multichannel Fiber Photometry System

Specifications

Features & Benefits

System Overview

Detecting activity changes of neurons in the central nervous system in real-time, the fiber photometry system sums up the overall fluorescence of neurons to express overall activity without reflecting the activity of individual neurons. RWD Fiber Photometry System utilizes the 410nm wavelength as the reference channel while the 470nm light source excites GCaMP. The significance of the reference channel lies in increasing self-control, reducing spontaneous fluorescence, eliminating signal artifacts caused by animal’s intense exercise and fiber winding, expressing two kinds of proteins at the same site, detecting levels of calcium change in different groups of neurons, and true recording and analysis of dual-color fluorescence signals.

Features & Benefits

LED excitation light sources

Two kinds of LED excitation light sources at 410 & 470 nm, of which 410 is the reference channel, allows for a more accurate fluorescence signal acquisition.

Software

The software has four pre-set fluorescence mode options, which can be applied to different experimental application scenarios.

Channels

It can support up to 9 channels, suitable for high-throughput calcium signal acquisition or simultaneous recording of multiple neural nucleus groups

Signals

High-performance and low noise CMOS camera can collect calcium fluorescence signals of multiple channels at up to 300 frames per second (fps).

Inputs

When the external event is marked, the time automatically inputs to achieve a synchronous recording with behavioral video, and the external stimulus time synchronization accuracy is up to 10ms.

Input ports

4 input ports support a variety of external signal input and automatic marking while 4 output ports support TTL signals to trigger external equipment.

Technical Specifications

Frame Rate of CMOS

0~300 FPS
sCMOS camera resolution
2048 * 2048 px
Exposure time setting range
1~100 ms
Fluorescence band
500-550 nm
Central wavelength of excitation light
410 nm, 470 nm
LED power adjustable percentage
0~100%
410nm LED Output Power Range
0~100 μW
470nm LED Output Power Range
0~100 μW

Publications & Articles

Cardiac Function