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New Article: Heterogeneity and dynamics of active Kras-induced dysplastic lineages from mouse corpus stomach

Scientists out of Vanderbilt and the University of North Carolina at Chapel Hill have established two separate organoid lines derived from active Kras-induced mouse stomach tissue. These organoid lines embody an in vitro system displaying characteristics of abnormal cells within the tissue known as dysplasia. The study published in Nature Communications provides further insights

By |2021-02-01T16:46:30-05:00February 1st, 2021|Categories: Articles, Cancer Research, Lab Equipment, Molecular|Tags: |Comments Off on New Article: Heterogeneity and dynamics of active Kras-induced dysplastic lineages from mouse corpus stomach

(July 8, 2020) WEBINAR: Reproducibility in Cellular Cancer Research: Providing Straightforward Solutions to a Sizeable Dilemma

There have been a number of published reports recently suggesting a substantial amount of cancer related studies published in high-impact scientific journals could not be reproduced outside of their originator laboratories. These discoveries are remarkably problematic as many of the drugs screened are being developed past the preclinical stage, into human testing

By |2020-11-26T15:38:47-05:00June 8th, 2020|Categories: Cancer Research, Event, Hypoxia, Molecular, Webinar|Tags: , , , , |Comments Off on (July 8, 2020) WEBINAR: Reproducibility in Cellular Cancer Research: Providing Straightforward Solutions to a Sizeable Dilemma

Counting Highly Dense Colonies

Perhaps you’ve been there - looking at a colony formation assay (CFA) where there are hundreds (or thousands) of colonies of various sizes and wondering “how can I possibly count all of these colonies accurately”? The logistical problem becomes even more difficult when you realize you should only be counting colonies over 30μm and

By |2021-03-02T14:07:34-05:00February 4th, 2019|Categories: Articles, Cancer Research, Molecular|Tags: |Comments Off on Counting Highly Dense Colonies

Re-evaluating manual colony counting: How automated counting is saving researchers time and effort

Manual colony counting method A typical manual counting scenario looks like this: The researcher finds an object and decides whether it is a colony. If it is determined to be a colony, the researcher then ascertains if it meets a minimum threshold to be a colony. If it does then 1 is added to

By |2021-03-02T13:43:05-05:00November 8th, 2018|Categories: Articles, Cancer Research, Lab Equipment, Molecular|Tags: |Comments Off on Re-evaluating manual colony counting: How automated counting is saving researchers time and effort
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