The SuperArgus PET/CT from Sedecal is a fully functional integrated system combining modern technologies for both PET and CT providing molecular imaging on a wide variety of pre-clinical animal models. The development of this system is a major breakthrough in high performance functional and molecular imaging technologies for biomedical research. The dual modality configuration delivers faster scan times with superior image resolution, improved localization and quantifiable data. The SuperArgus PET/CT has been designed with a user-friendly operator interface and easy animal positioning.
The new SuperArgus PET/CT incorporates state of the art technology as the latest evolution of the Argus PET/CT family of scanners.
The core of the new scanner combines the unique Phoswich PET detector technology, which provides true depth-of-interaction (tDOI), with the largest field of view on the market. The Super Argus PET/CT may be configured to image small animals such a mice (2 rings, rats and rabbits (2, 4 or 6 rings) all the way up to non-human primates, dogs, and pigs (6 rings).
Updates to the CT technology have focused on lower doses of radiation, faster scan times, higher resolution images and advanced applications.
The SuperArgus has been designed to meet the demanding needs of the busy laboratory with improved animal handing, including a multi-animal bed which allows for high throughput imaging of up to 10 mice at the same time.
SuperArgus PET/CT Main Achievements
- First combined PET/CT small animal scanner
- First small animal PET scanner with depth-of-interaction DOI (parallax correction)
- First small animal PET scanner with Full 3D True Response System Model in 3D OSEM reconstruction.
- First Ultra Fast 3D OSEM reconstruction without a cluster
- First and the only one with REAL TIME PET IMAGING
SuperArgus PET/CT/MR System Overview
The core of the SuperArgus PET/CT system is its Phoswich detector technology, which provides true depth-of-interaction (tDOI) or parallax-correcting capability, implemented through dual-scintillator phosphor sandwich detector modules.
Along with this advanced crystal technology, the SuperArgus PET/CT has the best in its class acquisition electronics with the following differentiating advantages:
- Highest resolution in the market
- Uniform resolution across the entire FOV
- Highest sensitivity per centimeter
- Highest dynamic time frame resolution: 2.5 ms
- Time stamp acquisition electronics
- Fully modular electronics.
- Parallel electronics acquisition, non multiplexing
- Superior image uniformity
- Faster scan times
- Fully integrated components
- Compact footprint
- High throughput, the highest NEC in the market for muti-animal studies
- Fast scanning with low dose
- 3 mice in the rabbit bed
- Zr 89 antibody compound
- 30 µCi activity per animal and 5 minutes acquisition
4 Bed System
ct scanners reviews
Video of PET in Awake Animals
Small ANIMALS RABBITS
|Phoswich modules with 4 lines of response virtually eliminate parallax effect (DOI) with 3D-OSEM reconstruction|
Higher detector sensitivity: two concentric detector rings instead of one
Resolution uniformity is considerably improved with DOI correction as radial source position increases.
More accurate quantitation of smaller ROIs at the edge of the FOV
System Matrix Response (SMR) corrects for:
SuperArgus PET/CT: tDOI in vivo Results
FORE=FSP 3D OSEM
2D OSEM 3D OSEM
|Model||Argus Compact||SuperArgus PET/CT 2r||SuperArgus PET/CT 4r||SuperArgus PET/CT 6r||SuperArgus PET/CT 2R||SuperArgus PET/CT 4R||SuperArgus PET/CT 6R||SuperArgus PET/CT 4P||SuperArgus PET/CT 6P|
|Animals||Mice only||Mice, rats and marmosets||Mice, rats and marmosets||Mice, rats and marmosets||Mice, rats, marmosets, rabbits (3 kg)||Mice, rats, marmosets, rabbits (3 kg)||Mice, rats, marmosets, rabbits (3 kg)||Non-human primates; canine; porcine, murine (10 kg)||Non-human primates; canine; porcine, murine (10kg)|
|Dynamic AFOV||100 mm||220 mm||220 mm||220 mm||350 mm||350 mm||350 mm||650 mm||650 mm|
|Static AFOV||100 mm||50 mm||100 mm||150 mm||50 mm||100 mm||151 mm||100 mm||150 mm|
|TFOV||50 mm||80 mm||80 mm||80 mm||120 mm||120 mm||120 mm||210 mm||210 mm|
|Bore size||55 mm||90 mm||90 mm||90 mm||160 mm||160 mm||160 mm||260 mm||260 mm|
|FOV||70 x 180 mm||120 x 350 mm||210 x 650 mm|
|Acquisition time||15 s||15 s||15 s|
|Spatial resolution||50 µm||15 µm||20 µm|
|Flat panel||CMOS and Cs plate||CMOS and Cs plate||CMOS and Cs plate|
|Detector Active Area||12 x 15 cm||23 x 15 cm||29 x 23 cm|
|Number of pixels||1944 x 1536||3072 x 1944||3888 x 3072|
|X Ray Energy peak||50 kV||130 kV||130 kV|
|Source spot||35 µm||7 to 100 µm||7 to 100 µm|
|Max Power||50 W||65 W||65 W|
|X Ray Protection||Auto shielded according FDA|
- Cardiac Function
- Pet/CT Imaging: PET/CT Imaging combines the functional nuclear imaging of positron emission tomography (PET) with the precision of an x-ray computed tomography (CT) scanner to produce accurate anatomic renderings allowing for visualizing metabolic or biochemical activity within the body. From a cardiovascular standpoint, PET/CT is a vital tool used for quantification of cardiac perfusion and assessment of coronary anatomy which has previously been underutilized due to costs and lack of readily available equipment.
- Cardiac Function
- Tumor Imaging
- Pet/CT imaging: PET/CT Imaging combines the functional nuclear imaging of positron emission tomography (PET) with the precision of an x-ray computed tomography (CT) scanner to produce accurate anatomic renderings allowing for visualizing metabolic or biochemical activity within the body. From an oncological standpoint, PET/CT allows for the accurate visualization of tumor specific metabolism as well as the capability of distinguishing malignant cells from adjacent normal tissue based on established differences in biochemical activity.
- Tumor Imaging
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