RFLSI III is based on the LSCI (Laser Speckle Contrast Imaging) technology design. With the advantages of its non-contact, high time resolution, high spatial resolution, and full-field rapid imaging, it provides a real-time dynamic blood flow monitoring and recording method for research in life sciences. The RFLSI III provides the basis for understanding tissue and organ pathological or physiological indexes vital data. Contrast agent is not needed, time resolution can be in milliseconds, spatial resolution can be in microns. RWD adopted a new all-in-one design to improve the operability for the user.