The γ-eye is the first and only SPECT scanner for real-time, in vivo screening of all single photon emission computed tomography (SPECT) isotopes. With its exchangeable collimators, small footprint, and field of view suitable for whole body mouse imaging, the γ-eye is a complete solution for all laboratories at any research stage.
The system is just 44cm x 46cm x 40cm in size, weighing less than 40kg. This makes it truly a desktop solution which can turn any space into an imaging lab. Despite its small footprint, the γ-eye’s has a sensitivity of 341 cps/MBq, spatial resolution up to 1.9mm and an energy resolution below 19%.
The animal handling system ensures the health and wellbeing of the imaging subject, while the Visual|eyes software suite provides a fully integrated, easy to use, platform for both image acquisition and data analysis.
Features & Benefits
Realtime imaging from time zero post injection
Immediate feedback to the user if the injection was successful and the radioisotope can be imaged within the imaging subject.
Frame rates down to 1 second
Combined with the features above, including real time, whole body, mouse imaging – these acquisition times would allow the kinetics and dynamic distribution of the imaging compound to be followed over time.
Small footprint (44cm x 46cm x 40cm), and weight less than 40kg
With its small size, and weight, the system is truly a benchtop system.
Easy to use analysis software and export capabilities including DICOM filed
Users can quickly and easily generate quantitative data on user defined ROIs within the analysis software. Or users can export the data and perform analysis in third party software.
Animal handling system with integrated anesthesia delivery, heated bed, and option to monitor vital signs
The user has the ability to monitor and maintain a stable physiological state of the imaging subject throughout the session. This allows consistency in data, as well as being important for the health and wellbeing of the animal.
Active field of view of 50mm x 100mm
This field of view is suitable for whole body mouse imaging, allowing for continuous and dynamic imaging in a single acquisition. This is necessary when examining the kinetics and temporal and spatial distribution of the imaging compound.
State-of-the-art technical characteristics:
- Sensitivity of 341 cps/MBq
- Spatial resolution up to 1.9mm
- eEnergy resolution below 19%
- Dynamic range from 30keV – 500keV
- Exchangeable collimators
Provides high sensitivity images across the whole field of view, over a broad range of signal intensities.
- Electrical requirements – 100-240 VAC
- PC connectivity – USB 2.0 Type A and Gb Ethernet
Allow the system to be positioned within any laboratory, animal facility, or clean room space – converting it into an imaging lab.
Anatomical mapping using artificially generated X-ray images.
The system does not product radiation, as it does not have an X-ray source; but anatomical information is still provided by the generated X-ray image.
Common imaging bed for all eye systems
Having a common imaging bed allows an animal to move from one eye system to another without moving. Images can be co-registered, allowing for multimodal imaging.
Models & Specifications
- Sensitivity 341 cps/MBq
- Spatial resolution up to 1.9mm @ 0mm
- Energy resolution below 19%
- Dynamic range from 30keV – 500keV
- Time frames, down to 1 second
- Integrated anesthesia
- Heated animal stage
- Vital sign monitoring
- Photodetectors – photomultiplier tubes
- Scintillators – CsI:Na
- Active field of view = 50mm x 100mm
- Anatomical mapping – artificial X-ray
- Exchangeable collimators – general purpose, high resolution, high sensitivity, high energy
γ-eye Imaging Gallery
SPECT can be used in cancer research applications in many ways: Confirm the presence of tumors Monitor the growth/size of tumors Detect metastasis Detect the expression of specific biomarkers
SPECT imaging of IN-111-Dotatate in mice with tumors. Image on the right includes protection of the kidneys, as seen by the reduced signal in this organ.
Targeted probes can be used to image specific biomarkers, for example:
Many SPECT compounds are being made which are considered to be both therapeutic and diagnostic at the same time.
Labelled compounds can be used to detect the pharmacokinetics, pharmacodynamics, and biodistribution of the compound over time after administration to the imaging subject.
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