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You are here:Home/Products/Oxford Optronix/Blood Flow Monitors – Oxford Optronix
Blood Flow Monitors – Oxford Optronix2018-05-17T18:17:27-05:00

OxyFlo™

Single-channel laser-Doppler tissue blood flow monitor/perfusion monitoring

  • Uncompromised reliability in continuous tissue blood flow assessment

  • Ideally suited to measurements of changing tissue blood flow in acute experimental models

  • Oxford Optronix - OxyFlo System Front
  • Oxford Optronix - OxyFlo System Back
  • Oxford Optronix - OxyFlo System Connector

OxyFlo™ Pro / Pro XL

Multi-channel laser-Doppler tissue blood flow monitors with integrated touch-screen

  • Uncompromised reliability in continuous tissue blood flow assessment

  • Ideally suited to measurements of changing tissue blood flow in acute experimental models

  • Enhanced productivity & features

  • Oxford Optronix - OxyFlo Pro System Front
  • Oxford Optronix - OxyFlo Pro System Back
  • Oxford Optronix - OxyFlo Pro System Connector

Overview

Perfusion by blood provides tissues with vital oxygen and nutrients, while removing waste products and distributing signaling molecules around the organism. The measurement of microvascular blood perfusion provides researchers with critical information in a number of research applications where blood supply has been disrupted.

Oxford Optronix blood flow monitors will be of interest therefore to life scientists wishing to directly and continuously measure local microvascular blood perfusion in in vivo models of ischemia-related disorders.

OxyFlo™ devices are laser Doppler flowmetry (LDF) monitors intended for monitoring of relative microvascular blood flow in living tissues.

Most applications are concerned with monitoring the competence of regional (microvascular) blood supply in specialties such as peripheral vascular disorders, cerebral perfusion monitoring in models of stroke and brain injury, tumour perfusion monitoring / angiogenesis, blood flow in free flaps and pedicle flaps, wound healing, surgery, transplantation and more.

Oxford Optronix Ltd. was founded when its current CEO pioneered the transition of the then nascent laser-Doppler flowmetry technology into a commercially viable product in the early 1990’s. Oxford Optronix remains a pioneer in the development of LDF technology and continues to set unrivaled standards of reliability, robustness and sensitivity, with the OxyFlo™ brand now well-established the world over in biomedical ischaemia research.

With the launch of OxyFlo™ Pro in 2013, a third-generation LDF platform, Oxford Optronix blends contemporary design, plug and play convenience and touch-screen operation to provide one of the most advanced and reliable blood flow monitors on the market.

Intended use statement:
OxyFlo™ and OxyFlo™ Pro are intended for laboratory, industrial and research use only.
OxyFlo™ and OxyFlo™ Pro are NOT intended for use in human subjects/patients.

Oxford Optronix - Made In Britain

Key Benefits

 

Continuous tissue blood flow assessment

Oxford Optronix high performance laser Doppler blood flow monitors provide uncompromised reliability in continuous tissue blood flow assessment and are ideally suited to measurements of changing tissue blood flow in acute experimental models.

 
 
 

Versatility

A range of probe types and probe formats provide support for a host of specialist disciplines and applications requiring both invasive or non-invasive tissue blood flow assessment.

 
 
 

ART

OxyFlo™ monitors incorporate proprietary artifact rejection technology (ART), effectively filtering out the presence of motion artifacts in the blood flow signal. This either substantially reduces, or in most cases, completely eliminates motion artifacts or ‘spikes’ in the blood flow data arising from sensor cable movement and/or regular tissue movement (e.g. due to breathing).

 
 
 

Plug and play

OxyFlo™ probes require no calibration procedures or configuration following one-time probe calibration. Probes supplied at the time of monitor shipment are supplied factor pre-calibrated.

 
 
 

Touch-screen display and interface

OxyFlo™ Pro models feature a touch-sensitive, high-contrast, 140º viewing-angle screen, which displays real-time data in both digital and graphical (trace) formats, and provides access to instrument/user settings.

 
 
 

Multi-channel productivity

The OxyFlo™ Pro is available as a 2-channel model or, uniquely, as a 4-channel device (OxyFlo™ Pro XL) capable of driving up to 4 probes simultaneously. This provides the flexibility to suit all needs, including the simultaneous monitoring of blood flow from multiple tissue sites (e.g. comparison of pathological versus control tissue sites).

 
 
 

Upgradeable

The OxyFlo™ Pro dual-channel model can be factory upgraded to a 4-channel device.

 
 
 

Single sensor multi-parameter monitoring

OxyFlo™ blood flow monitors have been specifically developed for use with OxyLite™ oxygen monitors. The combination of these two fibre optic measurement systems provides simultaneous tissue blood flow and oxygenation data from each ‘triple’ parameter combined sensor.

 
 
 

USB digital output

The entire range of Oxford Optronix tissue monitoring devices include a dedicated USB output that supports direct streaming of real-time recordings to a PC running the popular LabChart® Pro* charting software by ADInstruments. After installing a complimentary Add-on, LabChart will automatically identify the specific type and model of Oxford Optronix monitor and pre-load all the necessary configuration and channel settings, providing the ultimate in ‘plug and play’ convenience. For researchers wishing to make multi-parameter measurements, the Add-on supports multiple Oxford Optronix devices at the same time. Data acquisition and recording just got a whole lot easier!

 

ADInstruments LabChart

*LabChart version 8.0.4 or later required; PC/Windows only

 
 
 
 

Analogue data outputs

Continuous data recording to PC or Mac platforms is supported via standard analogue data outputs offering compatibility with third party data recording solutions.

 
 
 

2-year product warranty

Oxford Optronix monitors are now provided with a comprehensive 2-year manufacturer’s warranty, covering defects in material or in workmanship. An optional extended warranty package, providing up to 6 years of ‘peace of mind’ cover, including preventative maintenance servicing is available at the time of purchase.

 

Data Example

 

A Model of Middle Cerebral Artery Occlusion in Rat

A dedicated needle blood flow probe (product code ‘MNP100NX-3/10’), immobilized over a pre-determined region of the skull via a stereotactic apparatus was used to non-invasively measure cerebral cortex blood flow in response to temporary MCA occlusion. The trace shows continuous blood flow in arbitrary ‘blood perfusion units’ (BPU).

Click the data set image to view full screen.

 
Oxford Optronix - OxyFlo - Middle Cerebral Artery Occlusion in Rat
 

User Testimonials

 

“We have used OxyFlo probes for animal tumour studies and found them a great addition to the range of techniques that we use for studying the tumour microenvironment. The Oxford Optronix team is always extremely helpful, providing knowledgeable and thoughtful advice on every occasion. We will certainly carry on using them.”
– Dr Gillian Tozer, School of Medicine and Biomedical Sciences, University of Sheffield, UK

 

Applications and Literature Citations

 

OxyFlo™ blood flow monitors are employed the world over with an extensive citation record across a wide range of research applications summarized in the categories below. Browse the categories for a selection of recent publications, or click DOWNLOAD CITATIONS PDF for a complete list of all known literature citations.

 

Selected Citations

 
 
 

Vital Organs/Shock

 

Post EH, Su F, Hosokawa K, Taccone FS, Herpain A, Creteur J, Vincent JL, De Backer D, Changes in kidney perfusion and renal cortex metabolism in septic shock: an experimental study. J Surg Res (2017); 207, 145-154 [LINK]

Instrument cited: OxyFlo™ 4000

 

Brügger LE, Beldi G, Stalder M, Porta F, Candinas D, Takala J, Jakob SM, Postoperative splanchnic blood flow redistribution in response to fluid challenges in the presence and absence of endotoxemia in a porcine model. Shock (2012); 37(1), 116-21 [LINK]

Instrument cited: OxyFlo™ 4000

 

Cai RS1, Alexander MS, Marson L, Activation of somatosensory afferents elicit changes in vaginal blood flow and the urethrogenital reflex via autonomic efferents. J Urol (2008); 180(3), 1167-72 [LINK]

Instrument cited: OxyFlo™ 2000

 
 
 
 

Tumour/Cancer

 

Williams LJ, Mukherjee D, Fisher M, Reyes-Aldasoro CC, Akerman S, Kanthou C, Tozer GM, An in vivo role for Rho kinase activation in the tumour vascular disrupting activity of combretastatin A-4 3-O-phosphate. Br J Pharmacol (2014); 171(21), 4902-13 [LINK]

Instrument cited: OxyFlo™ 4000

 

Sersa G, Jarm T, Kotnik T, Coer A, Podkrajsek M, Sentjurc M, Miklavcic D, Kadivec M, Kranjc S, Secerov A, Cemazar M, Vascular disrupting action of electroporation and electrochemotherapy with bleomycin in murine sarcoma. Br J Cancer (2008); (2), 388-98 [LINK]

Instrument cited: OxyFlo™ 2000

 

Nikfarjam M, Muralidharan V, Malcontenti-Wilson C, Christophi C, Progressive microvascular injury in liver and colorectal liver metastases following laser induced focal hyperthermia therapy. Lasers Surg Med (2005); 37(1), 64-73 [LINK]

Instrument cited: OxyFlo™ 2000

 
 
 
 

Plastic Surgery/Wound Healing

 

Bagdas D, Cam Etoz B, Inan Ozturkoglu S, Cinkilic N, Ozyigit MO, Gul Z, Isbil Buyukcoskun N, Ozluk K, Gurun MS, Effects of systemic chlorogenic acid on random-pattern dorsal skin flap survival in diabetic rats. Biol Pharm Bull (2014); 37(3), 361-70 [LINK]

Instrument cited: OxyLab LDF™ 

 

Contaldo C1, Harder Y, Plock J, Banic A, Jakob SM, Erni D, The influence of local and systemic preconditioning on oxygenation, metabolism and survival in critically ischaemic skin flaps in pigs. J Plast Reconstr Aesthet Surg (2007); 60(11), 1182-92 [LINK]

Instrument cited: OxyFlo™ 2000

 

Harder Y, Contaldo C, Klenk J, Banic A, Jakob SM, Erni D, Preconditioning with monophosphoryl lipid A improves survival of critically ischemic tissue. Anesth Analg (2005); 100(6), 1786-92 [LINK]

Instrument cited: OxyFlo™ 2000

 
 
 
 

Physiology/Ischemia

 

Budgell BS, Sovak G, Soave D, TENS augments blood flow in somatotopically linked spinal cord segments and mitigates compressive ischemia. Spinal Cord (2014); 52(10), 744-8 [LINK]

 

Guerci P, Tran N, Menu P, Losser MR, Meistelman C, Longrois D, Impact of fluid resuscitation with hypertonic-hydroxyethyl starch versus lactated ringer on hemorheology and microcirculation in hemorrhagic shock. Clin Hemorheol Microcirc. (2014); 56(4), 301-17 [LINK]

 

Murnaghan M, Li G, Marsh DR, Nonsteroidal anti-inflammatory drug-induced fracture nonunion: an inhibition of angiogenesis? J Bone Joint Surg Am (2006); 88 Suppl 3, 140-7 [LINK]

 
 
 
 

Cerebral/Stroke/MCAO

 

Nakamura S, Walker DW, Wong FY, Cerebral haemodynamic response to somatosensory stimulation in near-term fetal sheep. J Physiol. (2017); 2017 595(4), 1289-1303 [LINK]

Instrument cited: OxyFlo™ 2000

 

Arpacı H, Çomu FM, Küçük A, Kösem B, Kartal S, Şıvgın V, Turgut HC, Aydın ME, Koç DS, Arslan M, Effects of lornoxicam and intravenous ibuprofen on erythrocyte deformability and hepatic and renal blood flow in rats. Drug Des Devel Ther (2016); 10, 2477-81 [LINK]

Instrument cited: OxyLab LDF™

 

Heikkinen R, Malm T, Heikkilä J, Muona A, Tanila H, Koistinaho M, Koistinaho J, Susceptibility to focal and global brain ischemia of Alzheimer mice displaying aβ deposits: effect of immunoglobulin. Aging Dis (2014); 5(2), 76-87 [LINK]

Instrument cited: OxyFlo™ 2000

 

Specifications for OxyFlo and OxyFlo Pro

GENERAL
DimensionsOxyFlo: 95mm (H) x 290mm (W) x 260mm (D)
OxyFlo Pro: 150mm (H) x 310mm (W) x 280mm (D)
WeightOxyFlo: 2kg / 4.5lbs
OxyFlo Pro: 4kg / 9lbs
Operating temperature10 – 30°C
Operating humidity0 – 70% (non-condensing)
Power requirementsOxyFlo: VAC 100-240V, 50-60Hz, 30W max
OxyFlo Pro: External PSU (100-240V/50-60Hz), 40W max
Fuse ratingOxyFlo: 2 x T1.6A
OxyFlo Pro: Not applicable
Number of sensors supported /
Number of channels
OxyFlo: 1
OxyFlo Pro: 2
OxyFlo Pro XL: 4
DisplayOxyFlo: 40 character alphanumeric OLED
OxyFlo Pro: High contrast 800 x 480 LCD touch-screen
Instrument configurationOxyFlo: Via function button at rear
OxyFlo Pro: Via touch-screen display
Analogue voltage outputsOxyFlo: 2 x male BNC connectors (2 outputs)
OxyFlo Pro: 1 x 15-pin D-type (4 outputs)
OxyFlo Pro XL: 2 x 15-pin D-type (8 outputs)
Laser typeTemperature-stabilized semi-conductor laser diode
Laser wavelength785 ±10nm
Laser classificationClass 1 (EN 60825-1:1994, 21 CFR 1040.10 and 1040.11)
 
PERFORMANCE
Mode of operationLaser Doppler flowmetry
Measurement units (displayed)0 – 9999 BPU (blood perfusion units)
Stability of reading± 5%
Sampling rate200Hz
Measurement averaging200ms (Flow); 5ms (Raw); 5s (ART); 200ms (Backscatter), rolling
Display update interval (numerical)2s (5s rolling averaged)
Probe identificationAutomatic; monitor stores one-time calibration
Probe calibrationFactory or user-calibrated using Oxford Optronix motility standard
Probe shelf-lifeUnlimited
ZeroingAutomatic, controlled
Default analogue data output range0 – 5V (= 0 – 5000 BPU or 0 – 100% Backscatter)
Analogue data output rate65Hz
 

Frequently Asked Questions

What physiological parameters does OxyFlo™ measure?

Oxford Optronix range of laser Doppler blood flow monitors are intended for the investigation of blood flow (also knows as blood perfusion or microvascular blood flow) in the microcirculation. The laser Doppler technique is well-established as the most convenient method for assessing tissue blood flow non-invasively and continuously. The technique allows continuous assessment of flow at one or more tissue sites via fibre-optic probes in contact with the tissue. The measurement of microvascular blood flow provides researchers with critical information in a number of research applications where blood supply has been disrupted (ischaemia). The technique is not intended for the measurement of blood flow rates in isolated blood vessels.

What makes the OxyFlo™ unique?

While substantially equivalent to other laser Doppler monitors on the market, OxyFlo™ monitors offer a number of distinguishing key features. Most notable of these is their ability to operate in conjunction with counterpart Oxford Optronix oxygen monitors for combined tissue oxygen, blood perfusion and temperature monitoring from a single sensor and therefore the same tissue micro-region. Furthermore, multi-channel OxyFlo™ Pro models offer an industry-first touch-screen display and user interface as well as an advanced, intelligent signal noise suppression output (ART™).

What are the typical applications for Oxford Optronix blood flow monitors?

OxyFlo™ blood flow monitors have proved popular in applications covering such disciplines as peripheral vascular disease, cerebral perfusion monitoring in models of stroke and brain injury, tumour perfusion monitoring / angiogenesis, blood flow in free flaps and pedicle flaps, wound healing, gastroenterology and more.

How do Oxford Optronix perfusion instruments work?

Oxford Optronix blood perfusion monitors utilize the well-established method of laser-Doppler Flowmetry (LDF) to provide a continuous measure of tissue blood blow. LDF works by illuminating a small region of tissue under observation with low power laser light from a sensor containing optical fibre light guides. Laser light from one fibre is directed towards the tissue and is scattered within the tissue. Some of the scattered laser light is incident upon moving red blood cells within the tissue and this light becomes Doppler-frequency shifted as a result. A second optical fibre collects this backscattered, Doppler-shifted light from the tissue and returns it to the detector within the monitor. The photo-detected signal comprises a broad spectrum of Doppler frequency shifted signals generated as a result of the movement of red blood cells within the tissue. Microvascular blood flow is electronically calculated as the product of mean red blood cell velocity and mean red blood cell concentration in the volume of tissue under illumination from the sensor.

What are the blood flow probes made of and how large are they?

All Oxford Optronix blood flow probes are constructed internally from glass or specialist plastic optical fibre light guides, terminating in needle, surface or other, specialist conformations designed to support the measurement of blood flow from almost any tissue. Probes are typically supplied in 3 m lengths and composed of specialist surgical steel, medical grade plastic and silicone materials.

Do Oxford Optronix blood flow monitors support the use of multiple probes at the same time?

Yes, the OxyFlo™ Pro is a two-channel monitor, while the OxyFlo™ Pro XL is a four-channel monitor capable of simultaneously driving and reading from up to 4 blood flow probes simultaneously. This allows the simultaneous collection of physiological blood flow data from up to four separate tissue sites at the same time, which may for example be useful when comparing pathological versus control tissue sites (e.g. contralateral cerebral perfusion). The ability to monitor from more than one tissue site can also be useful in mitigating for natural site to site blood flow variability by allowing multi-site signal averaging.

Are the blood flow probes supplied sterile?

No. While Oxford Optronix manufactures blood flow probes in a clean room environment, they are not supplied sterile. The blood flow probes can however be disinfected using 70% IMS or ethanol, and can be sterilized using industry-standard liquid sterilizers (e.g. Cidex®) or the low-temperature ethylene oxide gas method. Please note, neither Oxford Optronix blood flow probes, nor blood flow monitors possess CE or FDA regulatory approval for use in human subjects.

What is the sampling volume of the blood flow probes?

For most tissues, the mean sampling depth is in the region of 0.5 – 1.5 mm with a typical sampling volume in the region of 1 mm3. These values could be higher in regions where reduced photon absorption would be expected due to depleted erythrocyte concentration. These values have been obtained heuristically through many years of experience and are based on both in vitro observations and mathematical modelling of photon diffusion through ‘imaginary tissues’ using Monte-Carlo techniques.

What are the units of blood flow measurement?

The laser-Doppler technique for tissue blood flow measurement provides arbitrary, non-absolute, units for blood perfusion since the actual sampling volume/depth can only be determined by identifying which erythrocytes have interacted with the light remitted from the tissue, which in turn, is principally dependant on two parameters; namely, the optical scattering and the optical absorption coefficients of the tissue under observation. Since both of these coefficients are entirely dependent on the site of observation and perfusion of the microvasculature at the time of measurement, it is impossible to determine the actual sampling volume at any tissue site, and thus to express the measured component in absolute terms. The strengths of the laser-Doppler technique lie in observing continuous and quantifiable changes relative to baseline (control) measurements.

Do Oxford Optronix tissue blood flow monitors possess regulatory approval for clinical use?

No. At this time Oxford Optronix blood flow monitors and probes DO NOT possess CE or FDA regulatory approvals for use on human subjects.

Do you offer on-site demonstrations of Oxford Optronix instruments?

Yes, depending on geographical location we will try to arrange for an on-site demonstration of Oxford Optronix products by an experienced product specialist. Ideally, this will involve a full simulation of your application in order to maximize the benefit of the demonstration. On-site demonstrations are usually free of charge and can typically be arranged at 2 – 8 weeks notice. Alternatively, it is possible to arrange a limited trial of select monitors and sensors of interest.

Blood Flow Probes for OxyFlo™ and OxyFlo™ Pro

A range of fibre-optic based probes is available to support a diverse range of blood flow monitoring applications, including surface probes for (non-invasive) skin and tissue surface measurements, or needle type probes for direct (invasive) measurements from deeper tissue regions.

Reusable probes are supplied in a dedicated protective case for safe storage.

Oxford Optronix - OxyFlo - Blood flow probes for OxyFlo™ and OxyFlo™ Pro

Surface Type Blood Flow Probes

Standard Probe for Blood Flow from Tissue Surfaces
Product code ‘MSP100NX’

Oxford Optronix - OxyFlo - Product code 'MSP100NX'

These robust and easy-to-handle probes are ideal for measurements of microvascular blood flow on tissue surfaces. Tissue attachment via double-sided adhesive rings (product code ‘MSP140AR’).

Dimensions:

  • Head diameter: 17 mm
  • Head height : 8 mm
  • Total probe length: 3 m

Reusability: Unlimited

Digit Probe for Blood Flow from Rounded Surfaces
Product code ‘MSP110NX’

Oxford Optronix - OxyFlo - Product code 'MSP110NX'

Specifically developed with a curved geometry for measuring cutaneous blood flow in the digits. Tissue attachment via double-sided adhesive rings (product code ‘MSP140AR’).

Dimensions:

  • Head diameter: 17 mm
  • Head height : 10 mm
  • Total probe length: 3 m

Reusability: Unlimited

Miniature Probe for Blood Flow from Tissue Surfaces (suturable)
Product code ‘MSP300NX’

Oxford Optronix - OxyFlo - Product code 'MSP300NX'

Small and lightweight, suitable for non-invasive tissue surface blood flow monitoring and for semi-invasive monitoring of blood flow from muscle and internal organ surfaces. Tissue attachment via double-sided adhesive rings (product code ‘MSP140AR’) or by suture.

Dimensions:

  • Head diameter: 12 mm
  • Head height : 5 mm
  • Total probe length: 3 m

Reusability: Unlimited

Miniature Probe for Blood Flow from Tissue Surfaces (non-suturable)
Product code ‘MSP310NX’

Oxford Optronix - OxyFlo - Product code 'MSP310NX'

Small and lightweight, suitable for non-invasive tissue surface blood flow monitoring and for semi-invasive monitoring of blood flow from muscle and internal organ surfaces. Tissue attachment via double-sided adhesive rings (product code ‘MSP140AR’ see Accessories).

Dimensions:

  • Head diameter: 12 mm
  • Head height : 5 mm
  • Total probe length: 3 m

Reusability: Unlimited

Needle Type Blood Flow Probes

Standard Needle Blood Flow Probe
Product code ‘MNP100NX’

Oxford Optronix - OxyFlo - Product code 'MNP100NX'

Standard, robust needle probe for invasive blood flow measurements or non-invasive blood flow measurements from tissue surfaces. Typically positioned using an external clamp.

Dimensions:

  • Needle length: 30 mm
  • Needle diameter : 1 mm
  • Collar length: 16 mm
  • Collar diameter: 5 mm
  • Total probe length: 3 m

Reusability: Unlimited

Standard Needle Blood Flow Probe for MCAO
Product code ‘MNP100NX-3/10’

Oxford Optronix - OxyFlo - Product code 'MNP100NX-3/10'

Specifically conceived for cerebral microvascular blood flow measurements in MCAO and stroke applications.Typically positioned using an external clamp or using dedicated miniature holders (product codes ‘MH-10’ and ‘MH-05’, see Accessories).

Dimensions:

  • Needle length: 10 mm
  • Needle diameter : 1 mm
  • Collar length: 16 mm
  • Collar diameter: 5 mm
  • Total probe length: 3 m

Reusability: Unlimited

Fine Needle Blood Flow Probe
Product code ‘MNP110NX’

Oxford Optronix - OxyFlo - Product code 'MNP110NX'

This micro-needle probe has been developed for minimal tissue trauma during invasive insertion and is frequently used for measuring microvascular blood flow within muscle, tumours, internal organs and brain tissue. Typically positioned using an external clamp.

Dimensions:

  • Needle length: 30 mm
  • Needle diameter : 0.5 mm
  • Collar length: 16 mm
  • Collar diameter: 5 mm
  • Total probe length: 3 m

Reusability: Unlimited

Bent-Tip Needle Blood Flow Probe
Product code ‘MNP150NX’

Oxford Optronix - OxyFlo - Product code 'MNP150NX'

An angled probe tip facilitates blood flow measurements in specialist applications such as gingiva and nasal mucosa. Typically positioned using an external clamp.

Dimensions:

  • Needle length: 30 mm
  • Needle diameter : 1 mm
  • Collar length: 16 mm
  • Collar diameter: 5 mm
  • Total probe length: 3 m

Reusability: Unlimited

Specialist Blood Flow Probes

Single-Fibre Implantable Blood Flow Probe
Product code ‘MSF100NX’

Oxford Optronix - OxyFlo - Product code 'MSF100NX

This highly flexible probe consists of a 0.5mm diameter polymethyl methacrylate (plastic) fibre with a standard length of 30cm. Particularly useful for chronic implantation, the MSF100NX can be directly inserted into tissue using a standard 22G i.d. cannula. The small and light coupling bead minimizes the total weight of the implanted probe. Flow measurements are made by attaching the MSF Driver (product code ‘MSFD NX’, see Accessories Tab)

Dimensions:

  • Fibre length: 30 cm
  • Fibre diameter: 0.5 mm
  • Collar length: 8 mm
  • Collar diameter: 3 mm

Reusability: Limited

Bare-Type Blood Flow Probe
Product code ‘NX-BF/F’

Oxford Optronix - OxyFlo - Product code 'NX-BF/F'

This blood flow probe consists of a pair of 125 µm glass fibres for a combined diameter of less than 300 µm and a tip length of 60 mm. This probe type represents a minimally invasive and flexible alternative to the steel needle probes above and is particularly useful for direct insertion into tissue (via catheter or cannula) and measurement of microvascular blood flow from deeper tissue regions.

  • Tissue placement via introducer (e.g. Angiocath®)
  • Removable/adjustable Luer

Dimensions:

  • Tip diameter: approx. 300 µm
  • Exposed tip fibre length 6 cm
  • Total probe length: 2.5 m

Reusability: Limited

Optional Accessories

Value ADC

12-input analogue data acquisition module.
Oxford Optronix value data recording proposition, supplied with WinDAQ software by Dataq Instruments.

Oxford Optronix - OxyFlo - Value ADC

Single fibre adapter

Oxford Optronix specialist single fibre implantable blood flow probe type requires the connecting ‘MSFD NX’ adapter depicted.

Oxford Optronix - OxyFlo - Single fibre adapter

Calibration kit for blood flow probes

A motility standard comprising a solution of micro-spheres at a precisely controlled concentration and a probe positioning device together ensure highly reproducible blood flow probe calibration. Only required with stand-alone probe orders, where probes cannot be supplied pre-calibrated. Probes that accompany a blood flow monitor will be supplied factory pre-calibrated.

Oxford Optronix - OxyFlo - Calibration kit for blood flow probes

Adhesive rings

Double-sided adhesive rings used to secure surface blood flow probes to the skin. Sold in lots of 200.

Oxford Optronix - OxyFlo - Adhesive rings

Miniature needle probe holders

Miniature holders for use specifically with the MNP100NX-3/10 needle probe type probe. These are designed primarily for MCAO applications in rodents and can be attached directly to exposed skull using rapid-setting adhesive in order to firmly, yet reversibly secure the MNP100NX-3/10 probe type. Available in 5 mm or in 10 mm diameters and sold in packs of 5.

Oxford Optronix - OxyFlo - Miniature needle probe holders

BNC data cables

1 m BNC data cables for single channel OxyLite™ and OxyFlo™ monitors.
For data connection to third-party data recorder (e.g. PowerLab™ or Value ADC).

Oxford Optronix - OxyFlo - BNC data cables

BNC adapter cable for Pro models

1 m high density 15-pin D-connector to 4 BNC data adapter cable for OxyLite™ Pro and OxyFlo™ Pro monitors.
For data connection to third-party data recorder (e.g. PowerLab™ or ValueADC).

Oxford Optronix - OxyFlo - BNC adapter cable for Pro models

Measuring Tissue Perfusion and PO2 in Conscious Animals to Investigate Organ Failure

To watch the complete webinar click here