Living Systems Instrumentation designs, develops, and manufactures instruments for in vitro research studies of pressurized, perfused, cannulated blood vessels. These include vessel chambers and electro-mechanical apparatus for the measurement and control of pressure, flow rate and vessel dimensions. Living Systems also offers an array of laboratory equipment that are essential to any successful research project!

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Video Dimension Analyzer

This hardware edge detector tracks blood vessel diameter, and left and right wall thicknesses using an analog video signal. The principle of the instrument is based on sensing optical density changes of the vessel image at a chosen scan line seen on the TV monitor. The VDA-10 is well-suited for applications where a recording of blood vessel diameter and wall thickness is required.

The VDA-10 tracks vessels ranging from 50 to 350 µm in diameter. In some cases, particularly larger vessels, or those with thick walls, only the outside diameter can be measured. These measurements are displayed on digital panel meters, and analog voltage outputs provide signals suitable for recording using most popular lab data acquisition systems (e.g., DAQ-PRO-U). Changes in blood vessel dimensions (constriction or dilation) are followed in real time.

Applications

  • Record lumen diameter as a function of drug concentration, pressure, perfusate flow, membrane potential, and neurotransmitter release
  • Measure vasomotion, myogenic responses, and cardiac cell dimensions
  • Calculate wall tension and wall stress
  • Observe the influence of endothelium on vascular responses

Features

  • Continuous display of lumen diameter and wall thickness as vessel changes size
  • Eliminates subjectivity in measurement
  • Calibrated analog voltage outputs for data acquisition
  • Simplified operating controls including enhanced left & right vessel wall window start/width control
  • VCR recorded images may be analyzed for additional data
  • Video can be saved to VCR tape or computer disk using analog frame grabbers

Specifications 
Outputs—analog voltage signals 10 mV/µm
Digital meter reading 1 µm
Measurement precision 1–2 µm
Analog output signal update rate = 60/sec.
Power 100–120 V/60 Hz or 200–240 V/50 Hz – 1 A Max.
Dimensions 13.3 cm x 21.3 cm x 30.5 cm (HxWxD) 5.25 in x 8.4 in x 12 in (HxWxD)
Weight 3.4 kg/ 7.5 lbs

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Video Monitor, Flatscreen 19 inch Color

High quality display monitor can be used to display the video signal output from our VDA-10 video dimension analyzer.

Please note: Actual monitor may vary due to supplier variations.

Specifications
Input/Output Composite video (RCA to BNC connector included)
Display Size 13.3″
Resolution 1280×800

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Video Camera – HDMI

These high-quality video cameras are suitable for measuring blood vessel diameter using our video dimension analyzer (VDA-10), which only processes the luma portion of the video signal (“gray scale”), regardless of camera type (color or monochrome) used. With this camera package, the HDMI camera output is converted to the standard composite video signal that is delivered to our VDA-10 over a BNC cable.

This package contains the video camera, HDMI cable, and HDMI to composite (analog) video converter.

The HDMI signal does not go directly to a monitor; it must pass through the composite video converter to be processed by the VDA-10.

Please note: actual camera may vary due to supplier variations.

Specifications
Sensor Type 1/2.8″ CMOS (SONY: IMX136)
Video Output DVI (via HDMI connector)
Lens Mount C mount
Exposure Control Auto or Manual
Dimensions Camera Body: (WxHxD) 40 x 40 x 51.1 mm
Weight Camera Body: 4.1 oz (116 g)