New Journal Article – Cell Proliferation Detected Using [18F]FLT PET/CT as an Early Marker of Abdominal Aortic Aaneurysm
Abdominal aortic aneurysm (AAA) is a localized dilatation of the abdominal aorta which shows limited symptomology
Intermittent Hypoxia (OSA) and sustained hypoxia can prompt inter-tissue circadian clock misalignment
Circadian clocks are present in most cells of the body and act to coordinate human’s daily
New Journal Article – Circadian clock network desynchrony promotes weight gain and alters glucose homeostasis in mice
Circadian Rhythms lead to the coordination of a multitude of physiological, behavioural, and metabolic processes to
Applying Imaging to Study Infectious Diseases
Gayatri Gowrishankar, PhD Research Scientist Multimodality Molecular Imaging Lab Stanford University Alvaro
New Journal Article – Ultrasound-Induced Microbubble Cavitation via a Transcanal or Transcranial Approach Facilitates Inner Ear Drug Delivery
In a recent paper published in JCI Insight, researchers have demonstrated for the first time the
New Journal Article – Development of a Novel Superparamagnetic Nanoparticles to Quantify Nerve Density in Prostate Cancer and for Targeted Drug Delivery in the Same Model
In this journal article published in early February 2020 titled “Sight and switch off: Nerve density
New technology video: The CondoCell
How can researchers ensure their cells grow at optimal conditions when incubator doors open and close
In vivo tissue oxygenation: How do I know which method is best for my research?
There are a variety of ways that researchers today can measure oxygenation of tissue in vivo. Unfortunately,
How modern hypoxia chambers and chemically defined media are changing the face of cancer research
Cancer micro-environments are essential in understanding cancer malignancy and can provide accurate insights into how therapies targeting tumors
A Tale of Two Tubes: Exploring the Causes of Cardiovascular Disease from the Arteries to the Gut
The Integrative Cardiovascular Physiology laboratory at Colorado State University investigates the underlying causes of cardiovascular abnormalities
Imaging Solutions for Preclinical Research: Imaging Modalities and Their Applications
With the ever-growing preclinical imaging field, it is difficult to know which imaging modality is ideal
Understanding oxygen sensing in cells: A video lecture by Dr. Peter Ratcliffe
The lecture “Elucidation of oxygen sensing pathways in human and animal cells; implications for Physiology” by
Investigating mechanisms driving acute kidney injury arising from heart surgery and sepsis
A team of researchers and clinicians at the Florey Institute of Neuroscience and Mental Health are
Combating time and space issues in labs today: How a simple microscope is changing the way scientists do research
Combating time and space issue in labs todays: How a simple microscope is changing how scientists
Cancer Biology and Magnetic Resonance Imaging (MRI): The Gold Standard of Soft Tissue Imaging
Magnetic resonance imaging (MRI) is a technique that utilizes magnetic fields to create images of the
A versatile tool for 𝘪𝘯 𝘷𝘪𝘵𝘳𝘰 vascular research
Vascular function can be assessed in vitro using a myograph. Benchtop wire myograph systems consist of
Is 1 tesla enough: How low-field MRI is permitting more preclinical researchers to utilize this gold standard technique than ever before
In my day to day interactions, I come across numerous researchers who are not able to
The Importance of Cohousing During Telemetry Studies
Research animals must be housed under conditions that ensure their physiologic and behavioral needs are met.
PET/CT: Frequently Asked Questions
What is PET/CT Imaging? PET/CT imaging is the combination of two distinct imaging techniques. a What
Cancer biology and High-Frequency Ultrasound: non-invasive identification, visualization, and quantification in a wide variety of preclinical tumor models
Ultrasound has become a widely used preclinical imaging modality that can be used to visualize a
𝘐𝘯 𝘷𝘪𝘷𝘰 intermittent hypoxia: New chambers give researchers dynamic and controlled O₂ environment to enhance research
Intermittent hypoxia (IH), also referred to as hypoxia-reoxygenation, is a condition where periods of normal tissue
Investigating the role of metabolism in human induced pluripotent stem cell generation
This team of researchers in the Biology Department at Western University are investigating metabolic ways to increase efficiency
Counting Highly Dense Colonies
Perhaps you’ve been there - looking at a colony formation assay (CFA) where there are hundreds
A Non-Invasive Method to Assess Coronary Flow Reserve
Coronary flow reserve (CFR) is a measure of the ability of the coronary arteries to increase
Transverse Aortic Constriction (TAC): Why, how and the outcome as it relates to pressure overload-induced cardiac hypertrophy and/or heart failure
Chronic congestive heart failure, more commonly referred to as heart failure (HF), is a multifactorial cardiac