In vivo grafting of large, engineered heart tissue patches for cardiac repair
As the prevalence of heart failure continues to climb worldwide, most treatments that are currently available
Extra Virgin Olive Oil Phenols Vasodilate Rat Mesenteric Resistance Artery via Phospholipase C (PLC)-Calcium Microdomains-Potassium Channels (BKCa) Signals
The increase in wealth and standards of living around the world has resulted in a growing
Lifelong SIRT-1 Overexpression Attenuates Large Artery Stiffening With Advancing Age
In the United States, there is a progressive increase in cardiovascular diseases (CVDs) related to aging.
Heterogeneity and dynamics of active Kras-induced dysplastic lineages from mouse corpus stomach
Scientists out of Vanderbilt and the University of North Carolina at Chapel Hill have established two
Development of [¹⁸F]FPy-WL12 as a PD-L1 Specific PET Imaging Peptide
Programmed death ligand 1 (PD-L1) is the principal ligand of the programmed death one (PD-1) receptor
New Year, New HypoxyLab: Big Changes Coming to the System in 2021
Externally nothing was altered. The HypoxyLab continues to be a well designed, compact, and ergonomically friendly
Pressure Arteriography or Wire Myography? How to choose for your model.
Introduction The study of vascular function is central to understanding almost every aspect of physiology, pathophysiology
Transverse Aortic Constriction (TAC): Why, how and the outcome as it relates to pressure overload-induced cardiac hypertrophy and/or heart failure
Chronic congestive heart failure, more commonly referred to as heart failure (HF), is a multifactorial cardiac
Dual Energy X-Ray Absorptiometry How Does it Work?
Introduction Dual Energy X-Ray Absorptiometry (DXA/DEXA) is a technique used to assess body composition, providing measurements
The New Benchmark: How Vilber optics are revolutionizing gel and blot imaging for researchers
Whether detecting DNA, RNA, or proteins, it is challenging to find many biological publications today not using some form of gel and/or western
Live cell imaging is making research easier and adding efficiency to labs under COVID-19 restrictions
What is live cell imaging and what sets it apart? Live cell imaging is an umbrella
Tumor-Associated Macrophages Enhance Tumor Hypoxia and Aerobic Glycolysis
Tumor hypoxia and aerobic glycolysis are well-known resistance factors for anticancer therapies. Most tumour cells are
SimPET: A Preclinical PET Insert for Simultaneous PET/MR Imaging
Simultaneous Positron Emission Tomography (PET) and Magnetic Resonance Imaging (MRI) provides a unique non-invasive opportunity to
New Journal Article – Cell Proliferation Detected Using [18F]FLT PET/CT as an Early Marker of Abdominal Aortic Aaneurysm
Abdominal aortic aneurysm (AAA) is a localized dilatation of the abdominal aorta which shows limited symptomology
Intermittent Hypoxia (OSA) and sustained hypoxia can prompt inter-tissue circadian clock misalignment
Circadian clocks are present in most cells of the body and act to coordinate human’s daily
New Journal Article – Circadian clock network desynchrony promotes weight gain and alters glucose homeostasis in mice
Circadian Rhythms lead to the coordination of a multitude of physiological, behavioural, and metabolic processes to
Applying Imaging to Study Infectious Diseases
Gayatri Gowrishankar, PhD Research Scientist Multimodality Molecular Imaging Lab Stanford University Alvaro
New Journal Article – Ultrasound-Induced Microbubble Cavitation via a Transcanal or Transcranial Approach Facilitates Inner Ear Drug Delivery
In a recent paper published in JCI Insight, researchers have demonstrated for the first time the
New Journal Article – Development of a Novel Superparamagnetic Nanoparticles to Quantify Nerve Density in Prostate Cancer and for Targeted Drug Delivery in the Same Model
In this journal article published in early February 2020 titled “Sight and switch off: Nerve density
New technology video: The CondoCell
How can researchers ensure their cells grow at optimal conditions when incubator doors open and close
In vivo tissue oxygenation: How do I know which method is best for my research?
There are a variety of ways that researchers today can measure oxygenation of tissue in vivo. Unfortunately,
How modern hypoxia chambers and chemically defined media are changing the face of cancer research
Cancer micro-environments are essential in understanding cancer malignancy and can provide accurate insights into how therapies targeting tumors
Imaging Solutions for Preclinical Research: Imaging Modalities and Their Applications
With the ever-growing preclinical imaging field, it is difficult to know which imaging modality is ideal
Understanding oxygen sensing in cells: A video lecture by Dr. Peter Ratcliffe
The lecture “Elucidation of oxygen sensing pathways in human and animal cells; implications for Physiology” by
Combating time and space issues in labs today: How a simple microscope is changing the way scientists do research
Combating time and space issue in labs todays: How a simple microscope is changing how scientists