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Resources2019-03-01T16:12:51-04:00

Cancer biology and High-Frequency Ultrasound: non-invasive identification, visualization, and quantification in a wide variety of preclinical tumor models

Ultrasound has become a widely used preclinical imaging modality that can be used to visualize a variety of internal structures within small animal models with high resolution (down to 30µm). This provides researchers with primary structural information in real-time

By |March 7th, 2019|Animal Models, Articles, Cancer Research, Molecular, Mouse, Physiology, Rat|

𝘐𝘯 𝘷𝘪𝘷𝘰 intermittent hypoxia: New chambers give researchers dynamic and controlled O₂ environment to enhance research

Intermittent hypoxia (IH), also referred to as hypoxia-reoxygenation, is a condition where periods of normal tissue oxygen pressure (normoxia) cycle with periods of low tissue oxygen pressure (hypoxia). This alternating lack of oxygen is associated with various forms of

By |March 6th, 2019|Animal Models, Articles, Cancer Research, Hypoxia, Molecular, Mouse, Rat|

Webinar: How high frequency ultrasound imaging is supporting preclinical research applications

This free webinar hosted by Scintica Instrumentation introduced participants to some of the basics of high frequency ultrasound imaging and reviewed the most common preclinical research applications for this exciting technology. Our presenter, Ms. Tonya Coulthard, discussed

Investigating the role of metabolism in human induced pluripotent stem cell generation

This team of researchers in the Biology Department at Western University are investigating metabolic ways to increase efficiency of reprogramming adult cells to iPSCs. Embryonic stem cells are pluripotent, which means they can turn into any cell type found in the

By |February 21st, 2019|Articles, Cancer Research, Hypoxia, Lab Equipment, Molecular|

Webinar: Transverse Aortic Constriction: The Importance of Monitoring Surgical Outcomes

This free webinar hosted by Scintica Instrumentation reviewed with the viewer the importance of monitoring their surgical outcomes, specifically following transverse aortic constriction (TAC) Join Tonya Coulthard as she discussed some background information about the TAC

A Non-Invasive Method to Assess Coronary Flow Reserve

Coronary flow reserve (CFR) is a measure of the ability of the coronary arteries to increase blood flow to the myocardium via dilation during periods of stress.  CFR is reduced by age, as well as various disease states including

Changing how researchers think about MRI: Utilizing a simple to use, compact, MRI system to transform preclinical imaging

In this webinar Tonya Coulthard discussed features and benefits of the M-Series product line, focusing on the unique self-shielded compact design of the systems which allows them to be placed in any existing laboratory or animal facility

By |December 21st, 2018|Event, Imaging, Molecular, Webinar|

WEBINAR: What is hyperoxia, normoxia and hypoxia to cells: Why researchers should care about environmental oxygen and how it influences results

What oxygen levels are you using in your cellular research? Are your cells under hyperoxia, normoxia, hypoxia, or are you unsure? This free webinar hosted by Scintica Instrumentation provided our audience with an overview on the effects

By |December 21st, 2018|Cancer Research, Event, Hypoxia, Molecular, Webinar|

Transverse Aortic Constriction (TAC): Why, how and the outcome as it relates to pressure overload-induced cardiac hypertrophy and/or heart failure

Chronic congestive heart failure, more commonly referred to as heart failure (HF), is a multifactorial cardiac disease which can affect the heart both structurally and/or functionally thereby impairing its ability to properly fill and eject blood from the ventricles.

Normoxia isn’t normal: Conventional incubators generate more questions than they answer

Since the first CO2 incubators were made commercially available in the late 1960’s they have become a staple for researchers to grow and maintain cells in vitro. These chambers have been highly effective for this task; however, they do

By |November 26th, 2018|Articles, Cancer Research, Hypoxia, Lab Equipment, Molecular|

Re-evaluating manual colony counting: How automated counting is saving researchers time and effort

Manual colony counting method A typical manual counting scenario looks like this: The researcher finds an object and decides whether it is a colony. If it is determined to be a colony, the researcher then ascertains if it meets

By |November 8th, 2018|Articles, Cancer Research, Lab Equipment, Molecular|

Benchtop blood pressure: A fast, affordable and non-invasive technique

The capability to precisely and non-invasively measure the systolic and diastolic blood pressure, on top of heart rate and other blood flow parameters in rodents, can be of great clinical value to researchers. The non-invasive rat and mouse blood