The Indus Small Animal Telemetry System and associated wireless implants offer a simplified and cost-effective approach to studying physiology in conscious, unrestrained small animals. Scientists are able to monitor ECG, heart rate, core body temperature and activity in multiple, socially housed animals simultaneously.

 

The system consists of three core components:

 

The Indus Telemetry systems combines digital telemetry with wireless power technology.

Advantages of Telemetry – Conscious, unrestrained, long-term

The Three Rs of Animal Research

The 3Rs (Replacement, Reduction, and Refinement), introduced in 1959 by William Russell and Rex Burch and discussed more frequently in the past 15 years, serve as guidelines when designing experiments involving animals. The Doppler Flow Velocity System embraces these concepts in its design and everyday use.

Learn more about the 3Rs of Animal Research:

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Features that help you do better science…

Scientists can collect longitudinal data for longer duration and reuse implants in new subjects

Digital data transmission with inductive charging and battery backup to enable 24/7 digital data collection

Unique implant IDs permit multiple animals per cage, improving surgical recovery and optimizing throughput

Up to 3m recording range allows you to remove animals from the pads for short-term testing

 

Measurement Specifications – Biopotential (ECG) & Heart Rate

 

Sampling Frequency   1024Hz or 512Hz
Input Voltage Range   ±5mV
Electrode Type   Flexible, trimmable & repairable
Electrode Lead Length   20 cm, customizable
Heart Rate Reporting Frequency   1Hz when ECG active

 

Measurement Specifications – Activity 

 

Sensor Type   Onboard Accelerometer
Sampling Frequency   6 Hz
Max Reporting Frequency   1 sample/5 seconds (1x/5 sec)
Reporting Frequency Options   1x/5 sec, 1x/15 sec, 1x/30 sec, 1x/1 min,     1x/5 min, 1x/15 min
Resolution    0.1°C

 

Measurement Specifications – Temperature

 

Max Sampling Frequency   1 sample/0.5 seconds
Sampling Frequency   1x/0.5 sec, 1x/1 sec, 1x/5 sec, 1x/15      sec, 1x/30 sec, 1x/1 min, 1x/5 min,      1x/15 min
Range   0-50°C
Accuracy   0.1°C (Initial Calibration)

 

Measurement Specifications – Battery

 

Battery Type Rechargeable
Battery Life Off Charger   5 Days
Battery Charge Time   7 Days
Useful Device Life   > 1 Year

 

Wireless Data Recording and Charging

Advanced wireless technology allows one pad station to collect data from multiple subjects simultaneously. Included wireless implant chargers allow implants to record in subjects for extended periods. Analog outputs from the pads connect directly to any compatible data acquisition system (DAQ) using standard BNC connections.

 

Mouse Wireless Charger with Analog Output Specifications

 

Charging Capability One Unit will Recharge All Devices within a Standard Mouse Cage
Data Collection Capability One Unit will Collect Data from up to FOUR (4) Mice
Charging Distance Up to 5cm from Charger Surface
Charging Frequency 13.56MHz ISM Band
Power Source Standard USB Wall Charger, Input: Universal AC, Output: DC 5V 0.5A USB
Dimensions 250mm x 170mm x 20mm
Weight 0.4 Kg for Mouse Pad

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Wireless Implants

These small biocompatible devices are surgically implanted subcutaneously or within the subject’s peritoneal cavity, with ECG leads sutured to the pectoral muscles, one on each side of the chest. Once implanted, the devices can be wirelessly set to automatically collect ECG, heart rate, core temperature, and activity data at defined time periods and intervals.

 

Wireless Implants – General Specifications

 

Model  S18BTA
Volume  1.8 cc
Weight  ~2.7 grams
Body Shape  Cylindrical
Size 1 5.6mm diameter x 8.2mm thick

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Mouse Temperature/Activity Implants

Wireless Implants – General Specifications

 

Model S10TA
Volume ~1.2 cc
Weight ~2 grams
Body Shape Cylindrical
Size 15.6mm diameter

 

Wireless Data Recording and Charging

 

Rat Wireless Charger with Analog Output Specifications

 

Charging Capability One Unit will Recharge All Devices within a Standard Rat Cage
Data Collection Capability One Unit will Collect Data from up to TWO (2) Rats
Charging Distance Up to 5cm from Charger Surface
Charging Frequency 13.56MHz ISM Band
Power Source Standard USB Wall Charger, Input: Universal AC, Output: DC 5V 0.5A USB
Dimensions 500mm x 170mm x 20mm
Weight ~1 Kg

Wireless Implants

These small biocompatible devices are surgically implanted subcutaneously or within the subject’s peritoneal cavity, with ECG leads sutured to the pectoral muscles, one on each side of the chest. Once implanted, the devices can be wirelessly set to automatically collect ECG, heart rate, core temperature, and activity data at defined time periods and intervals.

Wireless Implants – General Specifications

 

Model S40BTA
Volume ~4.5 cc
Weight 4 grams
Body Shape Cylindrical
Size 24.6mm diameter x 9.5mm thick