In vitro
In vitro research is foundational to all biomedical research. The advancements made in studying cells, bacteria, and viruses are often the first strides into understanding the in vivo condition. We offer a laboratory solution for providing a stable physiologically relevant environment to cells as well as a solution to count colonies in colony forming assays.
ReCO2ver
Constant, ideal environment for optimal cell growth. At Baker, it is our job to deliver optimal “Environments for Science”TM. Our ReCO2ver and ReCO2ver Plus incubators have been designed with that in mind, providing precision control over the environmental conditions your cells require to thrive while delivering unprecedented recovery over those conditions after they have been interrupted.
Live Cell Imaging
Live-cell imaging itself has become a desired and often necessary analytical tool in many cell biology laboratories that operate in the field of neurobiology, developmental biology, pharmacology. Currently live-cell imaging is often difficult, because it required large costly high-end devices that are difficult to operate. The CytoSMART Lux2 is a highly compact, easy to use, and affordable inverted microscope for bright-field live cell imaging so it can be used in every biological laboratory.
Multimodal Imaging
VILBER Fusion systems are the ideal multimodal imaging platforms designed for molecular biology laboratories. They cover the spectrum of chemiluminescence, bioluminescence, multiplexing fluorescence and chemifluorescence applications. It offers the ultimate sensitivity, speed, and reaches the lowest limits of detection across all DNA, RNA and protein-based applications.
Gel Documentation
VILBER Gel Documentationsystems are the ideal imaging systems for gel documentation in any lab or core facility. VILBER offers a wide array of technologies to fit any application needed while offering unsurpassed sensitivity, speed, and the ability to reach the lowest limits of detection for DNA, RNA and protein applications.
PhO₂x Box
For cell researchers who have a standard CO2 incubator and want the option to perform studies controlling O2, there is the PhO2x Box. Perfect for short term hypoxia studies (where media does not need to be changed). The PhO2x Box grants researchers’ full control of O2 and CO2 while utilizing the temperature and humidity of the incubator.
Resipher
The Resipher turns a multi-well plate into a dynamic oxygen consumption reader. Based on a unique, patented technology, RESIPHER multi well plate analyzers offer unmatched performance in a compact package with low-power, plug-and-play USB connectivity. RESIPHER’s web-based, real-time logging and analysis software provides fast and easy data visualization and is extendable for customized real-time analysis.
Hypoxia Incubator and Workstation
For studies requiring a physiologically accurate atmosphere the HypoxyLab offers full control of O2, CO2, temperature and humidity. This ergonomically designed benchtop system is the only one of its kind to take measurements using the partial pressure of oxygen, making it the most reliable system for measuring oxygen on the market.
CondoCell
Luxury accommodation for cells. The CondoCell provides researchers 2 hypoxia options. 1) it allows them to take cells out of an existing hypoxia chamber and keeps them under those conditions for up to 20 mins and 2) an oxygen purging unit allows for a condo to be quickly purged of O2 for short term hypoxia studies.
Automated
Colony Counter
For those performing spheroids or tumor forming assays the GelCount is an automated colony counter that saves researchers from the painstaking task of potentially counting thousands of wells manually. Besides saving researchers large amounts of time and effort the system also calculates various growth dynamics, like diameter, which is not possible though manual counts alone.
Ex vivo
Ex vivo research is key to understanding specific organ and tissue function removed from other bodily stimuli. These conditions allow experimentation on an organism’s tissues under more controlled conditions than is possible in vivo. We currently offer many isolated heart, tissue, and vessel options.
Tissue Bath
The modular tissue bath system is suitable for use with smooth or striated muscle samples. Tissue and vessel ring holders enable the study of vessel rings and muscle tissue samples, adding to the versatility of the system. Force/displacement sensors quantify tissue reactivity, and the system can be coupled to a data acquisition system for data analysis.
Isolated Heart Systems
Isolated heart perfusion systems are ideal for ex vivo assessment of cardiac function. We offer gravitational, pump-controlled and compact systems for small animals. These systems can be configured as the Janicki-type Langendorff, where the heart is perfused through the aorta and the backward pressure forces flow into the coronary vessels, or the Neely-type working heart model.
Pressure and Wire Myographs
The small vessel myograph systems enables ex vivo assessment of vascular reactivity. These systems are suitable for pharmacological studies of dissected vascular rings. The measuring unit is removable, and can be used with a microscope to make mounting vessel rings easier. An isometric tension sensor quantifies vascular contraction and relaxation.