Immunology is the branch of biomedical sciences concerned with all aspects of the immune system in all multicellular organisms. It deals with the physiological functioning of the immune system in states of both health and diseases; malfunctions of the immune system in immunological disorders. With the rise in viral diseases like COVID-19, immunology research is at an all time high. Scintica Instrumentation offers researchers instruments for all stages of immunology research.
The Newton 7.0 is an innovative optical bioluminescence and fluorescence imaging system designed with the user in mind. It is ideal for in vivo, ex vivo and in vitro imaging applications, allowing for simultaneous imaging of multiple animals or samples at a time. This system is ideal for contextual analysis of immunological response through whole-organ fluorescent imaging. It combines the best optics and animal handling features for optimum scientific images and results. Capable for large throughput studies, up to 5 mice at a time.
PET/CT, is nowadays getting more and more relevant for the diagnosis of several infectious and inflammatory diseases and particularly for therapy monitoring.. In mouse models, PET/CT imaging can now be an affordable way to make the most of models relevant in cancer biology, cardiovascular research, immunology, neurological research, and developmental biology. Customizable radioactive tracers allow for the investigation of any compound within the mouse anatomy. Have the ability to view live imaging even in awake animals.
MRI is the gold standard in soft tissue imaging. The M-seriesTM compact MRI system provides anatomical and morphological images to pre-clinical researcher focused on a variety of disease models including immunology, cancer, neurology, cardiovascular, inflammation, obesity & diabetes, as well as specific organ diseases and developmental biology. The increasing complexity of in vivo imaging technologies, coupled with the development of cell therapies, has fuelled a revolution in immune cell tracking in vivo.
Hypoxia is a feature of physiological and pathological immunological research. The effect of hypoxia on immunity and inflammation will differ depending on the microenvironment and immune process. In immunological niches, like the bone marrow, placenta, lymphoid tissue and intestinal mucosa, physiological hypoxia controls innate and adaptive immunity by modulating immune cell proliferation, development and effector function, through transcriptional changes determined via hypoxia-inducible factors (HIF).