The article itself provides numerous justifications for why cancer investigators should recognize the importance of all micro-environments in their perspective studies. While this article is certainly topical for in vitro cancer-based researchers, it should also prove to be insightful for any cell-based investigators as well.
Information contained in the article includes:
Some key issues with growing cells in sub-optimal conditions.
How growing cells in a physiologically “natural” media plays a role in controlling specific cell types and end intentions of a study.
How growing cells in physiologically relevant atmospheric conditions is key to a variety of cellular processes which are essential to understanding cancer and tumor biology.
Examples looking at how media and atmospheric micro-environments can alter studies looking at the human immune system and cancers in particular.