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New Article: Heterogeneity and dynamics of active Kras-induced dysplastic lineages from mouse corpus stomach

Scientists out of Vanderbilt and the University of North Carolina at Chapel Hill have established two separate organoid lines derived from active Kras-induced mouse stomach tissue. These organoid lines embody an in vitro system displaying characteristics of abnormal cells within the tissue known as dysplasia. The study published in Nature Communications provides further insights

By |2021-02-01T16:46:30-05:00February 1st, 2021|Categories: Articles, Cancer Research, Lab Equipment, Molecular|Tags: |Comments Off on New Article: Heterogeneity and dynamics of active Kras-induced dysplastic lineages from mouse corpus stomach

New Year, New HypoxyLab: Big Changes Coming to the System in 2021

Externally nothing was altered. The HypoxyLab continues to be a well designed, compact, and ergonomically friendly hypoxia workstation perfect for any lab bench. All the changes themselves revolve around a complete redesign of the inner turret which houses the gas distribution system, temperature regulation, various sensors and HEPA filter. What does this mean for

By |2021-02-04T14:26:19-05:00January 25th, 2021|Categories: Articles, Cancer Research, Hypoxia, Lab Equipment, Molecular|Tags: |Comments Off on New Year, New HypoxyLab: Big Changes Coming to the System in 2021

(March 18, 2021) WEBINAR: How can (fluorescent) live-cell imaging be used for cell viability analysis?

Overview: In this free webinar, CytoSMART has partnered with prominent labs from academia to facilitate an open discussion about the use of live-cell imaging for viability analysis. We will be covering: The use of both brightfield and fluorescent live-cell imaging to analyze the effect of a treatment on cell viability. How cell viability

By |2021-03-01T13:17:43-05:00January 16th, 2021|Categories: Cancer Research, Event, Imaging, Lab Equipment, Molecular, Upcoming, Webinar|Tags: |Comments Off on (March 18, 2021) WEBINAR: How can (fluorescent) live-cell imaging be used for cell viability analysis?

(December 2, 2020) WEBINAR: Tips and Tricks for Successful Rat Telemetry Blood Pressure Recordings

Chronic blood pressure recordings from the abdominal aorta are commonplace in cardiovascular physiology, however the surgical implantation of catheters can be challenging. This webinar provided an overview of the surgical protocol that we recommend when implanting Kaha Sciences blood pressure telemeters. We also discussed some simple strategies to avoid common problems and the

By |2020-12-04T10:51:59-05:00October 21st, 2020|Categories: Animal Models, Cardiovascular Research, Event, Lab Equipment, Mouse, Physiology, Rat, Surgical Monitoring, Telemetry, Webinar|Tags: , |Comments Off on (December 2, 2020) WEBINAR: Tips and Tricks for Successful Rat Telemetry Blood Pressure Recordings

(November 11, 2020) WEBINAR: Introduction to Measurement of Tissue Oxygen in Rats Via Telemetry

Carbon paste electrodes connected to a potentiostat have been shown to provide stable measurement of tissue oxygen levels in vivo. Now wireless telemetry from Kaha Sciences allows the chronic long-term measurement of tissue oxygen in rats living in their home cages.  This webinar discussed how tissue oxygen measurements are made using carbon paste electrodes, how

By |2020-11-11T16:35:14-05:00October 9th, 2020|Categories: Animal Models, Cardiovascular Research, Event, Lab Equipment, Mouse, Physiology, Rat, Surgical Monitoring, Telemetry, Webinar|Tags: , |Comments Off on (November 11, 2020) WEBINAR: Introduction to Measurement of Tissue Oxygen in Rats Via Telemetry

(November 4, 2020) WEBINAR: Therapeutic Relevance of Elevated Blood Pressure After Ischemic Stroke in the Hypertensive Rats

Dr Pratik Thakkar from the University of Auckland presented data from their recent Hypertension publication where they used Cohousing mode (two telemeters in a single rat) to simultaneously record ICP, BP and brain tissue oxygen in a rat model of ischemic stroke. Spontaneously hypertensive rats were instrumented with telemeters to record BP, intracranial pressure,

By |2020-11-06T09:30:43-05:00October 9th, 2020|Categories: Animal Models, Event, Lab Equipment, Mouse, Rat, Surgical Monitoring, Webinar|Tags: , |Comments Off on (November 4, 2020) WEBINAR: Therapeutic Relevance of Elevated Blood Pressure After Ischemic Stroke in the Hypertensive Rats

(October 28, 2020) WEBINAR: Handling and Analyzing Large Telemetry Data Sets

Telemetry allows the long-term collection of data over days, weeks or months from animals in their home cages. Performing chronic studies presents a number of opportunities in terms of experimental design but also results in the collection of very large data sets. Large data sets come with challenges for the collection and analysis of

By |2020-10-29T10:22:19-04:00October 9th, 2020|Categories: Animal Models, Cardiovascular Research, Event, Lab Equipment, Mouse, Physiology, Rat, Surgical Monitoring, Telemetry, Webinar|Tags: , |Comments Off on (October 28, 2020) WEBINAR: Handling and Analyzing Large Telemetry Data Sets

(October 7, 2020) WEBINAR: Experimental Design for Chronic Telemetry Studies

Ensuring you collect the best and most physiologically accurate data from your chronic telemetry experiments requires careful planning and experimental design. This webinar gave an insight into the practical aspects of designing chronic animal experiments to set you on the best path for success. We discussed the benefits of chronic studies, how to select

By |2020-10-28T14:00:20-04:00October 7th, 2020|Categories: Animal Models, Event, Lab Equipment, Mouse, Rat, Surgical Monitoring, Telemetry, Webinar|Tags: , |Comments Off on (October 7, 2020) WEBINAR: Experimental Design for Chronic Telemetry Studies

(October 8, 2020) WEBINAR: Using EKG to Confirm MI in Mouse Model of Permanent LAD Occlusion

The mechanisms involved in the progression of heart failure includes cardiomyocyte death, initiation of the inflammatory response, and subsequent formation of a fibrotic scar. For this reason, diverse experimental models, such as cultured cardiac cells, isolated hearts, and animal models, have been created to mimic human myocardial infarction and heart failure. In a 2012

By |2020-10-29T15:44:53-04:00August 31st, 2020|Categories: Animal Models, Event, Lab Equipment, Mouse, Rat, Surgical Monitoring, Webinar|Tags: |Comments Off on (October 8, 2020) WEBINAR: Using EKG to Confirm MI in Mouse Model of Permanent LAD Occlusion
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