How can researchers ensure their cells grow at optimal conditions when incubator doors open and close at infrequent times on a daily basis? Is there an easy way to prevent contamination of key cell lines in a shared incubator? Want to keep cells at optimal conditions even outside of an incubator (CO2 or Tri-gas)? The
Combating time and space issue in labs todays: How a simple microscope is changing how scientists do research All researchers today, from grad students to principle investigators, are lacking 2 key factors that were widely available a generation ago. Today, both overall time and lab space have become a commodity in the research
Vascular function can be assessed in vitro using a myograph. Benchtop wire myograph systems consist of an organ bath, mounting wire or prongs, a micrometer, and a force transducer and amplifier to measure tension development in the tissue. This simple set-up is used in many fields of research, including pharmacology and vascular physiology. In
Research animals must be housed under conditions that ensure their physiologic and behavioral needs are met. These conditions influence animal well-being and the quality of data obtained throughout a study. Facilities are often designed with many of these factors in mind, including temperature and humidity control, lighting, noise and vibration. However, there are other
Each fall since 1950, the American Association for Laboratory Animal Science has held its annual National Meeting. During the five days of the meeting, members and nonmembers come together to enjoy the workshops, lectures, poster sessions, and exhibits. The program is designed to have topics relevant to the entire membership. The AALAS National
This team of researchers in the Biology Department at Western University are investigating metabolic ways to increase efficiency of reprogramming adult cells to iPSCs. Embryonic stem cells are pluripotent, which means they can turn into any cell type found in the adult body and are therefore critical for human development1. Stem cells show great promise in
Since the first CO2 incubators were made commercially available in the late 1960’s they have become a staple for researchers to grow and maintain cells in vitro. These chambers have been highly effective for this task; however, they do not take into account one significant factor - oxygen. Currently, there is a push from
Manual colony counting method A typical manual counting scenario looks like this: The researcher finds an object and decides whether it is a colony. If it is determined to be a colony, the researcher then ascertains if it meets a minimum threshold to be a colony. If it does then 1 is added to
The capability to precisely and non-invasively measure the systolic and diastolic blood pressure, on top of heart rate and other blood flow parameters in rodents, can be of great clinical value to researchers. The non-invasive rat and mouse blood pressure measurement consists of using a tail-cuff placed on the tail to occlude blood flow.
This free webinar hosted by Scintica Instrumentation provides an overview of different rodent anesthesia options and highlights the importance of rodent surgical monitoring and user safety. Topics discussed include: the benefits of inhalation versus injectable anesthesia, the physiological side effects of anesthesia, increasing Institutional Animal Care and Use Committee (IACUC) requirements,
