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Combating time and space issues in labs today: How a simple microscope is changing the way scientists do research

Combating time and space issue in labs todays: How a simple microscope is changing how scientists do research Β Β Β Β  All researchers today, from grad students to principle investigators, are lacking 2 key factors that were widely available a generation ago. Today, both overall time and lab space have become a commodity in the research

By |2019-06-11T09:09:34-04:00June 10th, 2019|Categories: Articles, Cancer Research, Lab Equipment, Molecular, Physiology|Comments Off on Combating time and space issues in labs today: How a simple microscope is changing the way scientists do research

Cancer Biology and Magnetic Resonance Imaging (MRI): The Gold Standard of Soft Tissue Imaging

Magnetic resonance imaging (MRI) is a technique that utilizes magnetic fields to create images of the anatomy and the physiological processes within the body. Specifically, MRI, the gold standard in soft tissue imaging, offers researchers the ability to distinctly contrast between normal and pathological tissue. When it comes to the strengths of MRI in

By |2019-05-21T17:12:43-04:00May 21st, 2019|Categories: Animal Models, Articles, Cancer Research, Imaging, Molecular, Mouse, MRI, PET/CT, Rat|Tags: , , , , , , , , , , , , , , , , , , , , |Comments Off on Cancer Biology and Magnetic Resonance Imaging (MRI): The Gold Standard of Soft Tissue Imaging

A versatile tool for π˜ͺ𝘯 𝘷π˜ͺ𝘡𝘳𝘰 vascular research

Vascular function can be assessed in vitro using a myograph. Benchtop wire myograph systems consist of an organ bath, mounting wire or prongs, a micrometer, and a force transducer and amplifier to measure tension development in the tissue. This simple set-up is used in many fields of research, including pharmacology and vascular physiology. In

By |2019-05-15T12:48:53-04:00May 14th, 2019|Categories: Animal Models, Articles, Cardiac Function, Cardiovascular Research, Lab Equipment, Mouse, Physiology, Rat|Comments Off on A versatile tool for π˜ͺ𝘯 𝘷π˜ͺ𝘡𝘳𝘰 vascular research

Is 1 tesla enough: How low-field MRI is permitting more preclinical researchers to utilize this gold standard technique than ever before

In my day to day interactions, I come across numerous researchers who are not able to fully utilize MRI systems as they would like or cannot see themselves using this technology even though it could immensely help their research. The reasons for this are numerous but often fall into 1 of 3 categories. Price

By |2019-05-06T13:05:16-04:00May 6th, 2019|Categories: Animal Models, Articles, Cancer Research, Imaging, Molecular, Mouse, MRI, PET/CT, Rat|Comments Off on Is 1 tesla enough: How low-field MRI is permitting more preclinical researchers to utilize this gold standard technique than ever before

The Importance of Cohousing During Telemetry Studies

Research animals must be housed under conditions that ensure their physiologic and behavioral needs are met.Β  These conditions influence animal well-being and the quality of data obtained throughout a study. Facilities are often designed with many of these factors in mind, including temperature and humidity control, lighting, noise and vibration.Β  However, there are other

By |2019-04-29T11:39:20-04:00April 29th, 2019|Categories: Animal Models, Articles, Cardiac Function, Cardiovascular Research, Lab Equipment, Mouse, Physiology, Rat, Telemetry|Comments Off on The Importance of Cohousing During Telemetry Studies

PET/CT: Frequently Asked Questions

What is PET/CT Imaging? PET/CT imaging is the combination of two distinct imaging techniques. a What is PET Imaging? PET, or positron emission tomography, is a look at the metabolic or biochemical activity present in a given anatomical region using radiotracers. a What is a radiotracer? A radiotracer is a chemical compound in which

By |2019-04-11T16:07:11-04:00April 11th, 2019|Categories: Animal Models, Articles, Cancer Research, Imaging, Mouse, PET/CT, Rat|Comments Off on PET/CT: Frequently Asked Questions

Cancer biology and High-Frequency Ultrasound: non-invasive identification, visualization, and quantification in a wide variety of preclinical tumor models

Ultrasound has become a widely used preclinical imaging modality that can be used to visualize a variety of internal structures within small animal models with high resolution (down to 30Β΅m). This provides researchers with primary structural information in real-time allowing for the non-invasive quantification of organ/tumor parameters in both two- and three-dimensions, as well

By |2019-04-11T16:08:26-04:00March 7th, 2019|Categories: Animal Models, Articles, Cancer Research, Imaging, Molecular, Mouse, Physiology, Rat, Ultrasound|Comments Off on Cancer biology and High-Frequency Ultrasound: non-invasive identification, visualization, and quantification in a wide variety of preclinical tumor models

𝘐𝘯 𝘷π˜ͺ𝘷𝘰 intermittent hypoxia: New chambers give researchers dynamic and controlled Oβ‚‚ environment to enhance research

Intermittent hypoxia (IH), also referred to as hypoxia-reoxygenation, is a condition where periods of normal tissue oxygen pressure (normoxia) cycle with periods of low tissue oxygen pressure (hypoxia). This alternating lack of oxygen is associated with various forms of the respiratory illness, sleep apnea. Those afflicted with sleep apnea can see oxygen fluctuate dramatically

By |2019-03-06T12:29:31-04:00March 6th, 2019|Categories: Animal Models, Articles, Cancer Research, Hypoxia, Molecular, Mouse, Rat|Comments Off on 𝘐𝘯 𝘷π˜ͺ𝘷𝘰 intermittent hypoxia: New chambers give researchers dynamic and controlled Oβ‚‚ environment to enhance research

Investigating the role of metabolism in human induced pluripotent stem cell generation

This team of researchers in theΒ Biology Department at Western UniversityΒ are investigating metabolic ways to increase efficiency of reprogramming adult cells to iPSCs. Embryonic stem cells are pluripotent, which means they can turn into any cell type found in the adult body and are therefore critical for human development1. Stem cells show great promise in

By |2019-03-01T15:28:47-04:00February 21st, 2019|Categories: Articles, Cancer Research, Hypoxia, Lab Equipment, Molecular|Comments Off on Investigating the role of metabolism in human induced pluripotent stem cell generation

Counting Highly Dense Colonies

Perhaps you’ve been there - looking at a colony formation assay (CFA) where there are hundreds (or thousands) of colonies of various sizes and wondering β€œhow can I possibly count all of these colonies accurately”? The logistical problem becomes even more difficult when you realize you should only be counting colonies over 30ΞΌm and

By |2019-03-01T15:29:17-04:00February 4th, 2019|Categories: Articles, Cancer Research, Molecular|Comments Off on Counting Highly Dense Colonies