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Animal Models

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In vivo tissue oxygenation: How do I know which method is best for my research?

There are a variety of ways that researchers today can measure oxygenation of tissueΒ in vivo. Unfortunately, while a range of options do exist, choosing which technology to use to measure tissue oxygenation is often difficult, even to those who have years of experience in the field. Here, we cover the four most prominent ways researchers

By |2019-10-18T17:12:50-04:00October 18th, 2019|Categories: Animal Models, Articles, Micro-Vascular Flow, Mouse, Physiology, Rat, Telemetry, Tissue Oxygen|Comments Off on In vivo tissue oxygenation: How do I know which method is best for my research?

A Tale of Two Tubes: Exploring the Causes of Cardiovascular Disease from the Arteries to the Gut

The Integrative Cardiovascular Physiology laboratory at Colorado State University investigates the underlying causes of cardiovascular abnormalities in the settings of obesity and nutrient excess. Obese individuals are at an increased risk for developing cardiovascular disease (CVD)1. Prior to overt clinical manifestation of CVD, the arteries of obese individuals (and other at-risk populations) begin to

By |2019-10-15T14:26:38-04:00September 11th, 2019|Categories: Animal Models, Articles, Cardiac Function, Cardiovascular Research, Fish, Mouse, Physiology, Rat|Comments Off on A Tale of Two Tubes: Exploring the Causes of Cardiovascular Disease from the Arteries to the Gut

American Heart Association – Nov 14 – 17, 2019 – Philadelphia, PA

The scientific sessions from the American Heart Association is instrumental in shaping the future of cardiovascular science and medicine. Highlights include: Late-Breaking Science FIT/Early Career Programming Frontiers in Science Summits State of the Art Cardiovascular Care Cardiovascular Clinical Nursing Symposium Abstract Oral and Poster Sessions CME and MOC Credits Available

By |2019-09-09T13:47:34-04:00September 9th, 2019|Categories: Animal Models, Cancer Research, Cardiac Function, Cardiovascular Research, Conference, Confocal, Event, Fish, Imaging, Mouse, MRI, PET/CT, Physiology, Rat, Ultrasound, Upcoming|Comments Off on American Heart Association – Nov 14 – 17, 2019 – Philadelphia, PA

Imaging Solutions for Preclinical Research: Imaging Modalities and Their Applications

With the ever-growing preclinical imaging field, it is difficult to know which imaging modality is ideal for your experiment. This brief overview aims to help researchers optimize their experiments and their funding by choosing ideal imaging modalities for their prospective publications. Β Modalities discussed include: Magnetic Resonance Imaging (MRI) Positron Emission Tomography (PET) Computed Tomography

By |2019-08-28T10:28:24-04:00August 27th, 2019|Categories: Animal Models, Articles, Cancer Research, Cardiovascular Research, Confocal, Fish, Imaging, Mouse, MRI, PET/CT, Physiology, Rat, Ultrasound|Comments Off on Imaging Solutions for Preclinical Research: Imaging Modalities and Their Applications

WEBINAR: Novel Nanoparticle-based Contrast Agents for Preclinical MRI Studies at 1T: Research Applications in Placental Disorders

This webinar considered a new class of targeted, liposomal-gadolinium MRI contrast agents that do not cross the placental barrier for preclinical studies of placental vascular architecture and placental accreta, or invasive placentation. These studies are conducted on a 1T permanent magnet MRI instrument which has high sensitivity for this gadolinium-based contrast

By |2019-09-30T13:52:09-04:00August 26th, 2019|Categories: Animal Models, Event, Imaging, Molecular, Mouse, MRI, Rat, Webinar|Comments Off on WEBINAR: Novel Nanoparticle-based Contrast Agents for Preclinical MRI Studies at 1T: Research Applications in Placental Disorders

Investigating mechanisms driving acute kidney injury arising from heart surgery and sepsis

A team of researchers and clinicians at the Florey Institute of Neuroscience and Mental Health are investigating ways to reduce the incidence of kidney injury resulting from heart surgery and sepsis. Acute kidney injury is when our kidneys suddenly stop working. This happens in up to 30% of patients after heart surgery. Up to

By |2019-07-12T15:48:24-04:00July 12th, 2019|Categories: Animal Models, Articles, Micro-Vascular Flow, Mouse, Physiology, Rat, Tissue Oxygen|Comments Off on Investigating mechanisms driving acute kidney injury arising from heart surgery and sepsis

World Molecular Imaging Congress – Sept 4 – 7, 2019 – Montreal, QC

The WMIC changes location every year to draw thousands of attendees and abstract submitters, highly respected presenters and top industry representatives from around the world. As the WMIC is education and abstract- driven, it provides a distinctive platform for scientists and clinicians with diverse backgrounds to interact and present cutting-edge advances in molecular

By |2019-07-08T15:11:29-04:00July 8th, 2019|Categories: Animal Models, Cancer Research, Cardiac Function, Cardiovascular Research, Conference, Confocal, Event, Fish, Imaging, Mouse, MRI, PET/CT, Physiology, Rat, Ultrasound, Upcoming|Comments Off on World Molecular Imaging Congress – Sept 4 – 7, 2019 – Montreal, QC

Cancer Biology and Magnetic Resonance Imaging (MRI): The Gold Standard of Soft Tissue Imaging

Magnetic resonance imaging (MRI) is a technique that utilizes magnetic fields to create images of the anatomy and the physiological processes within the body. Specifically, MRI, the gold standard in soft tissue imaging, offers researchers the ability to distinctly contrast between normal and pathological tissue. When it comes to the strengths of MRI in

By |2019-05-21T17:12:43-04:00May 21st, 2019|Categories: Animal Models, Articles, Cancer Research, Imaging, Molecular, Mouse, MRI, PET/CT, Rat|Tags: , , , , , , , , , , , , , , , , , , , , |Comments Off on Cancer Biology and Magnetic Resonance Imaging (MRI): The Gold Standard of Soft Tissue Imaging

A versatile tool for π˜ͺ𝘯 𝘷π˜ͺ𝘡𝘳𝘰 vascular research

Vascular function can be assessed in vitro using a myograph. Benchtop wire myograph systems consist of an organ bath, mounting wire or prongs, a micrometer, and a force transducer and amplifier to measure tension development in the tissue. This simple set-up is used in many fields of research, including pharmacology and vascular physiology. In

By |2019-05-15T12:48:53-04:00May 14th, 2019|Categories: Animal Models, Articles, Cardiac Function, Cardiovascular Research, Lab Equipment, Mouse, Physiology, Rat|Comments Off on A versatile tool for π˜ͺ𝘯 𝘷π˜ͺ𝘡𝘳𝘰 vascular research

Is 1 tesla enough: How low-field MRI is permitting more preclinical researchers to utilize this gold standard technique than ever before

In my day to day interactions, I come across numerous researchers who are not able to fully utilize MRI systems as they would like or cannot see themselves using this technology even though it could immensely help their research. The reasons for this are numerous but often fall into 1 of 3 categories. Price

By |2019-05-06T13:05:16-04:00May 6th, 2019|Categories: Animal Models, Articles, Cancer Research, Imaging, Molecular, Mouse, MRI, PET/CT, Rat|Comments Off on Is 1 tesla enough: How low-field MRI is permitting more preclinical researchers to utilize this gold standard technique than ever before